Sionna Therapeutics Inc (SION)

Currency in USD
45.09
+1.79(+4.13%)
Closed·
44.77-0.32(-0.71%)
·
Unusual trading volume
Trading near 52-week High
SION is not included in our AI-picked strategies. See which stocks are.
Fair Value
Day's Range
42.6246.10
52 wk Range
9.3946.10
Key Statistics
Prev. Close
43.3
Open
44.23
Day's Range
42.62-46.1
52 wk Range
9.39-46.1
Volume
768.53K
Average Vol. (3m)
317.84K
1-Year Change
350.9%
Book Value / Share
6.88
Fair Value
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Fair Value Upside
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SION Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
49.11
Upside
+8.92%
Members' Sentiments
Bearish
Bullish
ProTips
2 analysts have revised their earnings downwards for the upcoming period

Sionna Therapeutics Inc News & Analysis

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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Buy
Technical Indicators
Strong Buy
Moving Averages
Strong Buy

Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmembrane conductance regulator (CFTR) that has completed Phase 2 trial; navocaftor (SION-3067), a potentiator that has completed Phase 2 trial; SION-109, an intracellular loop 4 directed CFTR corrector that has completed Phase 1 trial; SION-2851, a TMD1-directed CFTR corrector that has completed Phase 1 trial; SION-451, which is nucleotide-binding domain 1 stabilizer in Phase 1 trial; and SION-719, which is nucleotide-binding domain 1 stabilizer in Phase 2a proof-of-concept trial. The company was formerly known as Sling Therapeutics, Inc. and changed its name to Sionna Therapeutics, Inc. in July 2021. Sionna Therapeutics, Inc. was incorporated in 2019 and is headquartered in Waltham, Massachusetts.

Compare SION to Peers and Sector

Metrics to compare
SION
Peers
Sector
Relationship
P/E Ratio
−27.0x−4.3x−0.5x
PEG Ratio
−0.29−0.090.00
Price / Book
6.6x5.3x2.6x
Price / LTM Sales
-10.7x3.2x
Upside (Analyst Target)
15.3%69.2%45.7%
Fair Value Upside
Unlock2.6%4.8%Unlock

Analyst Ratings

9 Buy
0 Hold
1 Sell
Ratings:
10 analysts
Overall Consensus
Strong Buy

Analysts 12-Month Price Target:

Average 49.11
(+8.92% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
Guggenheim
Buy50.00+10.89%45.00MaintainMar 02, 2026
Citizens
Buy63.00+39.72%-New CoverageFeb 24, 2026
Raymond James
Buy53.00+17.54%45.00MaintainJan 05, 2026
LifeSci Capital
Buy60.00+33.07%-New CoverageDec 23, 2025
RBC Capital
Sell24.00-46.77%-DowngradeDec 01, 2025

Earnings

Latest Release
Mar 02, 2026
EPS / Forecast
-0.46 / -0.71
Revenue / Forecast
-- / --
EPS Revisions
Last 90 days

SION Income Statement

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FAQ

What Is the Sionna Therapeutics (SION) Stock Price Today?

The Sionna Therapeutics stock price today is 45.09 USD.

What Stock Exchange Does Sionna Therapeutics Trade On?

Sionna Therapeutics is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Sionna Therapeutics?

The stock symbol for Sionna Therapeutics is "SION."

What Is the Sionna Therapeutics Market Cap?

As of today, Sionna Therapeutics market cap is 1.95B USD.

What Is Sionna Therapeutics's Earnings Per Share (TTM)?

The Sionna Therapeutics EPS (TTM) is -1.88.

When Is the Next Sionna Therapeutics Earnings Date?

Sionna Therapeutics will release its next earnings report on May 18, 2026.

From a Technical Analysis Perspective, Is SION a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Strong Buy.

How Many Times Has Sionna Therapeutics Stock Split?

Sionna Therapeutics has split 0 times.

How Many Employees Does Sionna Therapeutics Have?

Sionna Therapeutics has 59 employees.

What is the current trading status of Sionna Therapeutics (SION)?

As of Apr 16, 2026, Sionna Therapeutics (SION) is trading at a price of 45.09 USD, with a previous close of 43.30 USD. The stock has fluctuated within a day range of 42.62 USD to 46.10 USD, while its 52-week range spans from 9.39 USD to 46.10 USD.

What Is Sionna Therapeutics (SION) Price Target According to Analysts?

The average 12-month price target for Sionna Therapeutics is 49.11 USD, with a high estimate of 63 USD and a low estimate of 24 USD. 9 analysts recommend buying the stock, while 1 suggest selling, leading to an overall rating of Strong Buy. The stock has an +8.92% Upside potential.

What Is the SION Premarket Price?

SION's last pre-market stock price is 44.28 USD. The pre-market share volume is 416.00, and the stock has decreased by 0.98, or 2.26%.

What Is the SION After Hours Price?

SION's last after hours stock price is 44.77 USD, the stock has decreased by -0.32, or -0.71%.
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